4800 front
Directed by Don E. FauntLeRoy
Produced by Alison Semenza
Written by David Olson
Starring Crystal Allen
Linden Ashby
Danny Midwinter
John Rhys-Davies
Music by Peter Meisner
Cinematography Don E. FauntLeRoy
Editing by Scott Conrad
Original channel SciFi Channel
Production company Stage 6 Films
Hollywood Media Bridge
Castel Film Romania
Release dates February 28, 2009
Running time 88 minutes
Country United States
Language English
Preceded by Anaconda 3: Offspring (2008)
Followed by Lake Placid vs. Anaconda (2015)

Anacondas: Trail of Blood, (also known as Anaconda 4, Anaconda 4: Trail of Blood and Anacondas 4: Trail of Blood), is a 2009 made-for-television horror film directed by Don E. FauntLeRoy. The film is a direct sequel to Anaconda 3: Offspring and the fourth and final installment in the Anaconda-franchise. It premiered on the SciFi Channel on February 28, 2009 and was released to DVD on June 2, 2009.[1]

The film was followed by the spin-off crossover-film Lake Placid vs. Anaconda (2015).


A baby anaconda, which was captured at the end of the previous film, is being used for experiments by a scientist. He creates a hybrid of the blood orchids from Borneo that enabled the anaconda to grow so large and live so long, and creates a serum for cell regeneration. When he disappears, the anaconda escapes the cage and kills the scientist in a mine filled with blood orchids. Murdoch, a billionaire suffering from bone cancer, sends a team to find him and the serum because that serum can cure him. He also tells them to be careful of Dr. Amanda Hayes, and to kill her if needed. As Dr. Amanda Hayes, the sole survivor of the previous snake attack, and two officers also go in search of the scientist, determined to destroy the serum and kill the snake.

On the way they meet Alex, a trekker who appears lost in the Romanian Carpathians, while doing a pathology project. When they discover the blood orchids in the mine, Amanda sets the explosives to destroy the orchids, but she is attacked by the anaconda that kills two officers, but manages to evade it. As Amanda and Alex leaves the mine, Amanda is knocked unconscious and Alex escapes to get more help. Meanwhile, two groups encounter more people (Scott, Jackson, Patrick, Wendy and Heather) who are looking for the base camp of fellow scientists but get dragged into the search for the snake. Due to the serum, the anaconda can no longer die without significant damage to its internal organs. During the course of the film, Heather falls ill due to a spider bite. The next day, most of the people are attacked and eaten by the snake. It first kills one of the hunters working for Murdoch. When the other hunters find Hayes and Jackson's group, they shoot an already injured Patrick, wounded by the snake, and Wendy for trying to escape.

The snake finds them and devours Leila and Hakeem. Amanda and Jackson are forced to find the serum, and are accompanied by two henchmen of Eugene to find it. They put up at the scientist's house. There the two find the serum but keep it hidden. The anaconda strikes the house and devours one gunman, and while the other is trying to fight it off, Amanda and Alex escape. Jackie corners them, but is taken by surprise by Jackson. The snake attacks Jackie and he accidentally blows himself up with a grenade. It then chases Amanda and Scott. Scott sacrifices himself to the snake to buy time for Amanda to run. In one attempt to destroy the snake Amanda throws a gasoline tank at the snake then explodes the gasoline tank, which then splits the snake in two, but the snake regenerates.

Back at the base camp, Murdoch appears, but is in for a rude shock when he sees that his arch enemy is also there, and that Eugene has joined hands with the latter. Seeing the melee they are in, Jackson stabs Eugene, makes him shoot Murdoch's rival and then fights Armon but is shot by the latter. As he is going to kill Jackson, Amanda shoots Armon to death. Murdoch arrives, demanding that Amanda give him the serum. As they do that, he keeps his word not to kill them, and tells them to leave. As the remaining survivors leave in the jeep, Murdoch injects himself with the serum and discovers that it works, but the snake kills him. As Amanda finally destroys the orchids for good, she, Jackson, Alex and Heather try to escape in a jeep as the anaconda pursues them but they are attacked by Eugene, who had clung on the back of the vehicle and grabs Jackson. Amanda kicks him out of the car with two grenades in hand. While the snake devours him, it is blown to bits. As Amanda, Jackson, Alex and Heather leave, the anaconda who seems to have regenerated, appears and slithers into the forest.



The film was shot back-to-back with Anaconda 3: Offspring in Romania (Bucharest, Danube Delta, etc.)[2][3] When the film was first announced, David Hasselhoff was slated to appear to reprise his character of Hammett from the third film.


Like the previous film, it was poorly received, for low-budget special effects, a weak plot, and wooden acting. However, it received better reviews than did Anaconda 3: Offspring.


  1. Anacondas: Trail of Blood (2009)

External links


Anaconda (1997) • Lake Placid (1999) • Anacondas: The Hunt for the Blood Orchid (2004) • Lake Placid 2 (2007) • Anaconda 3: Offspring (2008) • Anacondas: Trail of Blood (2009) • Lake Placid 3 (2010) • Lake Placid: The Final Chapter (2012) • Lake Placid vs. Anaconda (2015) • Lake Placid: Legacy (2018)


Anaconda - Original Motion Picture Soundtrack (1997) • Lake Placid - Original Motion Picture Soundtrack (1999) • Anacondas: The Hunt for the Blood Orchid - Original Motion Picture Soundtrack (2004)


Quake Anaconda Mod (1997) • Croc Drop (1999) • Anacondas Arcade Game (2004) • Anacondas 3D Adventure Game (2004) • Lake Placid 2: Croc Alley (2007) • Snakes on a Babe (2008)


Anaconda: The Writer's Cut (2014)


Giant AnacondaGiant CrocodileWasp (Amazon)Monkey (Borneo)Crocodile (Borneo)Leeches (Borneo)Spider (Borneo)


AmazonBlack LakeMaineBorneoWexel HallWexel Hall PharmaceuticalsRomaniaClear Lake


Terri FloresDanny RichPaul SeroneDr. Steven CaleWarren WestridgeGary DixonDenise KalbergMateoPoacherJack WellsKelly ScottHector CyrSheriff Hank KeoughMrs. Delores BickermanDeputy Sharon GareWalt LawsonStephen DanielsJanineMyra OkuboDeputy BurkeDeputy StevensOfficer CoulsonParamedicState TrooperKevinAirplane PilotBill JohnsonSamantha "Sam" RogersCole BurrisGail SternDr. Jack ByronGordon MitchellTran WuDr. Ben DouglasJohn LivingstonChristian Van DykeLawyerCEOLead Lopak HunterLopak HunterBartenderKong

Cast & Crew

Jennifer LopezIce CubeJon VoightEric StoltzJonathan HydeOwen WilsonKari WuhrerVincent CastellanosDanny TrejoFrank WelkerHans Bauer